Add/Remove Portlets from the Left/Right Slots
Open the Zope Management Interface window and click on the Properties tab. Edit the fields in the left_slots and/or right_slots windows as desired.
An out-of-box Plone site comes with the following portlet fields lines:
left_slots
here/portlet_navigation/macros/portlet
here/portlet_login/macros/portlet
here/portlet_recent/macros/portlet
here/portlet_related/macros/portlet
right_slots
here/portlet_review/macros/portlet
here/portlet_news/macros/portlet
here/portlet_events/macros/portlet
here/portlet_calendar/macros/portlet
These lines can be deleted or moved as desired.
Portlets can be customized for any folder by opening the window for that folder in the ZMI window and clicking on the Properties tab. Under "To add a new property", enter left_slots or right_slots, select "lines" for type, and enter one of the above portlet instructions in the value field. Click the Add button. Note that whatever property you add here can easily be deleted, so trial and error is a safe proposition.

